J Physiol, 591(18):4655-66
The dideaza analogs include, for example, 1,5-dideaza, 5,10-dideaza, 8,10-dideaza, and 5,8- dideaza analogs of folate, folinic acid, pteropolyglutamic acid, and folate receptor-binding pteridines such as tetrahydropterins, dihydrofolates, and tetrahydrofolates
[11] Serious but uncommon events include immediate-type hypersensitivity with urticaria, bronchospasm, or anaphylaxis, and delayed eosinophilic myositis
These definitive findings underscore L-carnitine's vital, irreplaceable role in supporting heart muscle energy, which is a critical consideration for patients desperately trying to manage the severe cardiovascular symptoms of dysautonomia and POTS
In other words, people with PVD may be able to walk farther and longer if they take carnitine, particularly proprinylcarnitine